People with
Lynch syndrome are at higher risk for some other cancers stomach, uterine, pancreatic . About 50 to 70 percent of people with Lynch syndrome create colon cancer. making them a group in whom preventive measures can be more basically studied than the general population because the disease occurs earlier and progresses more quickly.
In the new study, published in The Lancet, researchers randomly assigned 861 people in 16 countries who had Lynch syndrome to take aspirin tablets a day or identical-looking placebos. After slightly over years, there was no difference between the groups in cancer incidence. But after about years, there was a difference. Eighteen
people taking aspirin developed cancer compared with 30 taking a placebo. Not every participant stayed with the program. When only those who took aspirin for years or more were thought about, the reduction in cancer rate was about 60 percent.
About
15 percent of cancers in the general population result from mutations in the genes affected in Lynch syndrome a kind of DNA spell-checker known as mismatch-repair. Other studies, however, have shown that aspirin lowers the risk of colon cancer resulting from other mutations, .
However, aspirin has side effects of them is bleeding. If they give all patients aspirin, there were 10,000 cases of cancer are preventable, but there's 1,000 people suffering from intestinal bleeding, they said. In another study in 2010 also concluded, aspirin reduce the risk of death from all cancers when taken 75 mg per day. Burn advised to consult your doctor in the event you need to take aspirin every day. But if there is a history of cancer of the relatives, can be thought about to take precautions in this way, they said.
Those at high risk of colon cancer, for example, people with lynch syndrome,there is a history of heredity, or individuals who frequent contact with carcinogens can reduce risk by
taking aspirin everyday. This was evidenced by a study conducted in England by Sir John Burn of Newcastle University. They and his team studied 861 people with Lynch syndrome, a crooked to suffer from cancer due to heredity. Every day Burn and his team gave the patients 600 mg of aspirin. They said at the finish of the age of 40 or 50 years the cancer prevention benefits of aspirin is stronger when the patient began to eat them. The study found that Among a group of people with what is called Lynch syndrome who took every day aspirin for years or more were 60 percent less likely to create cancer of the rectum or colon than those not taking the drug.
